Quetiapine Fumarate
Quetiapine fumarate is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder (MDD). It works by modulating dopamine D2 and serotonin 5-HT2A receptors, helping to balance neurotransmitter activity in the brain. This mechanism effectively reduces psychotic symptoms such as hallucinations, delusions, and disorganized thinking in individuals with schizophrenia. Additionally, quetiapine is widely prescribed for bipolar disorder, where it helps manage both manic and depressive episodes, promoting mood stabilization. It is also used as an adjunctive therapy for major depressive disorder (MDD), particularly in cases where other antidepressants alone are insufficient. Due to its sedative properties, it is often beneficial for patients experiencing insomnia and anxiety associated with mood disorders.
One of quetiapine’s key advantages is its low risk of extrapyramidal symptoms (EPS), such as tremors and rigidity, compared to older antipsychotics. However, it is associated with side effects such as drowsiness, dizziness, weight gain, and metabolic changes, including an increased risk of diabetes and high cholesterol. Due to its sedative effects, it is often prescribed at lower doses for sleep disorders in some patients. While quetiapine is effective for treating multiple psychiatric conditions, regular monitoring is recommended to manage potential metabolic side effects. Despite these considerations, quetiapine remains a widely used and well-tolerated antipsychotic, providing effective symptom relief and improving overall quality of life for individuals with schizophrenia, bipolar disorder, and depression.
Document Support
- Certificate of Analysis (COA)
- Method of Analysis (MOA)
- Route of Synthesis (ROS)
- Good Manufacturing Practice (GMP) Compliance
- International Organization for Standardization (ISO) Certification
- Open Drug Master File (OP-DMF)
- Stability Data & Reports
Pharmacopoeia | IP / USP / EP / BP |
---|---|
CAS No. | 111974-72-2 |
Formula | C46H54N6O8S2 |
Molecular Weight | 883.1 |
Quetiapine Fumarate
Quetiapine fumarate is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder (MDD). It works by modulating dopamine D2 and serotonin 5-HT2A receptors, helping to balance neurotransmitter activity in the brain. This mechanism effectively reduces psychotic symptoms such as hallucinations, delusions, and disorganized thinking in individuals with schizophrenia. Additionally, quetiapine is widely prescribed for bipolar disorder, where it helps manage both manic and depressive episodes, promoting mood stabilization. It is also used as an adjunctive therapy for major depressive disorder (MDD), particularly in cases where other antidepressants alone are insufficient. Due to its sedative properties, it is often beneficial for patients experiencing insomnia and anxiety associated with mood disorders.
One of quetiapine’s key advantages is its low risk of extrapyramidal symptoms (EPS), such as tremors and rigidity, compared to older antipsychotics. However, it is associated with side effects such as drowsiness, dizziness, weight gain, and metabolic changes, including an increased risk of diabetes and high cholesterol. Due to its sedative effects, it is often prescribed at lower doses for sleep disorders in some patients. While quetiapine is effective for treating multiple psychiatric conditions, regular monitoring is recommended to manage potential metabolic side effects. Despite these considerations, quetiapine remains a widely used and well-tolerated antipsychotic, providing effective symptom relief and improving overall quality of life for individuals with schizophrenia, bipolar disorder, and depression.
Document Support
- Certificate of Analysis (COA)
- Method of Analysis (MOA)
- Route of Synthesis (ROS)
- Good Manufacturing Practice (GMP) Compliance
- International Organization for Standardization (ISO) Certification
- Open Drug Master File (OP-DMF)
- Stability Data & Reports
Pharmacopoeia | IP / USP / EP / BP |
---|---|
CAS No. | 111974-72-2 |
Formula | C46H54N6O8S2 |
Molecular Weight | 883.1 |