Lurasidone hydrochloride is an atypical antipsychotic medication primarily used for the treatment of schizophrenia and bipolar disorder. It works by modulating dopamine D2 and serotonin 5-HT2A receptors, helping to restore chemical balance in the brain. This mechanism helps reduce hallucinations, delusions, and disorganized thinking in individuals with schizophrenia while also stabilizing mood in those with bipolar depression. Unlike some older antipsychotics, lurasidone has a lower risk of sedation and weight gain, making it a preferred option for many patients requiring long-term treatment. Additionally, it has antidepressant effects due to its action on serotonin receptors, which makes it particularly effective in bipolar disorder with depressive episodes.

One of the key advantages of lurasidone is its once-daily dosing, which improves treatment adherence and convenience for patients. It is generally well-tolerated, but common side effects include nausea, dizziness, sleep disturbances, and restlessness. Unlike some other antipsychotics, it has a lower likelihood of causing metabolic side effects, such as weight gain or increased blood sugar levels, making it a safer choice for patients at risk of diabetes or cardiovascular issues. However, because it may still cause extrapyramidal symptoms (EPS) like restlessness or muscle stiffness, careful monitoring is recommended. Despite these considerations, lurasidone remains an effective and well-balanced option for managing psychotic disorders and mood instability, helping individuals achieve better mental health and daily functioning.

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Pharmacopoeia	IN-HOUSE
CAS No.	367514-88-3
Formula	C28H37ClN4O2S
Molecular Weight	529.1